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Nefopam HCL 30 mg & Paracetamol 325 mg Tablets

This combination tablet offers a synergistic non-opioid pain relief formulation with Nefopam Hydrochloride, a centrally acting analgesic, and Paracetamol (Acetaminophen), a well-established antipyretic and analgesic. It is ideal for the treatment of moderate to severe acute pain without the sedative or addictive risks associated with opioid medications.

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Description

Indications:

This combination is indicated for the management of moderate to severe pain, including musculoskeletal pain, postoperative pain, dental pain, and neuralgia. It is especially effective when non-opioid pain relief is preferred.

Mechanism of Action:

  • Nefopam HCL acts centrally by inhibiting the reuptake of serotonin, dopamine, and norepinephrine, altering pain perception without opioid-like sedation or respiratory depression.
  • Paracetamol enhances analgesic and antipyretic activity by inhibiting prostaglandin synthesis in the central nervous system.

Key Benefits:

  • Dual mechanism provides synergistic pain relief
  • Non-opioid, non-steroidal formulation minimizes dependency risks
  • Suitable for post-operative and chronic pain management
  • Fast-acting with sustained relief

Dosage & Administration:

Recommended dosage is one tablet up to three times a day, depending on the severity of pain and patient response. Always follow physician’s instructions.

Precautions & Warnings:

  • Avoid alcohol and CNS depressants during use
  • Use with caution in patients with liver or kidney impairment
  • Not recommended during pregnancy or lactation unless advised by a physician
  • May cause dizziness or nausea in some patients

Side Effects:

Possible side effects include dry mouth, nausea, sweating, drowsiness, or nervousness. Rarely, allergic skin reactions or gastrointestinal disturbances may occur.

Storage:

Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.

Export & Contract Manufacturing

We offer this product for export across regulated and semi-regulated markets. All batches are manufactured under WHO-GMP certified facilities following stringent quality controls and international documentation standards, including COAs, MSDS, and stability data upon request. We support global pharmaceutical distributors, hospital procurement, and government tenders with customized supply solutions.

Third-Party & Private Label Options

Available under flexible third-party manufacturing and private label arrangements. We provide end-to-end support from formulation to packaging design, regulatory documentation, and international logistics. Branding and packaging can be fully customized to suit your domestic or international market needs.

Leading Manufacturer and Exporter of Pharmaceuticals Across Continents

Aetos Life Care is a trusted manufacturer and exporter of high-quality generic and specialty medicines, serving over 40 countries across Latin America, Africa, Asia, Europe, and the CIS region. We have a strong presence in key markets, including Iraq, Jordan, Saudi Arabia, UAE, Ukraine, Kazakhstan, Venezuela, Ecuador, and more. Backed by 15 WHO-GMP accredited facilities designed to meet EU-GMP standards, we ensure the highest quality, safety, and compliance in every product we deliver.

Iraq, Jordan, Riyadh (Saudi Arabia), Dubai (UAE)

Ukraine, Kazakhstan, Turkmenistan, Tajikistan

Venezuela, Ecuador, Peru, Paraguay, Panama, Costa Rica, El Salvador

Cameroon, South Sudan, Angola

Myanmar