Description
Mechanism of Action:
✔ Directly inhibits factor Xa, preventing the conversion of prothrombin to thrombin.
✔ Reduces blood clot formation while maintaining normal circulation.
✔ Lowers the risk of stroke and embolism in atrial fibrillation patients.
Indications:
✔ Stroke Prevention in Atrial Fibrillation – Reduces the risk of stroke in non-valvular atrial fibrillation patients.
✔ Deep Vein Thrombosis (DVT) & Pulmonary Embolism (PE) – Prevents and treats blood clots in the legs and lungs.
✔ Post-Surgical Thromboprophylaxis – Recommended after hip or knee replacement surgery.
Key Benefits:
✅ Safer alternative to warfarin with fewer bleeding risks.
✅ Fixed oral dosing without frequent monitoring.
✅ Fast onset of action for immediate clot prevention.
✅ Effective for long-term anticoagulation therapy.
Dosage & Administration:
- Recommended Dosage: 2.5 mg or 5 mg twice daily, as prescribed.
- Route of Administration: Oral.
- Food Intake: Can be taken with or without food.
Precautions & Warnings:
- Increases bleeding risk – should be used cautiously in patients with bleeding disorders.
- Not recommended for patients with severe liver disease or prosthetic heart valves.
- Use with caution in renal impairment.
- Avoid use with strong CYP3A4 and P-gp inhibitors (e.g., ketoconazole, ritonavir).
Possible Side Effects:
- Easy bruising or prolonged bleeding.
- Nausea or mild stomach pain.
- Anemia or fatigue.
- Rare cases of severe bleeding or internal hemorrhage.
Storage & Packaging:
- Store at room temperature below 30°C.
- Available in blister packs and bottle packaging.
- Custom packaging options available for bulk orders.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP accredited facilities, ensuring compliance with EU-GMP quality standards.
Global Export & Supply:
Aetos Life Care exports Apixaban 2.5 mg, 5 mg Tablets to Latin America, Africa, Asia, Europe, and CIS countries, ensuring high-quality and cost-effective anticoagulation therapy worldwide.
