Description
Mechanism of Action:
Clonidine acts on alpha-2 adrenergic receptors in the brainstem, reducing norepinephrine release, thereby lowering blood pressure and reducing withdrawal symptoms.
Indications:
✔ Hypertension (High Blood Pressure)
✔ Attention Deficit Hyperactivity Disorder (ADHD)
✔ Opioid & Nicotine Withdrawal Symptoms
✔ Menopausal Hot Flashes
Key Benefits:
✅ Effectively lowers blood pressure by reducing nerve signals
✅ Helps manage ADHD symptoms by improving focus and impulse control
✅ Reduces withdrawal symptoms in opioid or nicotine dependence
✅ Can be used as adjunct therapy for resistant hypertension
Dosage & Administration:
- Clonidine 0.1 mg: Starting dose for hypertension and withdrawal symptoms
- Clonidine 0.2 mg – 0.3 mg: For patients requiring higher dose titration
- Route of Administration: Oral
- Food Intake: Can be taken with or without food
Precautions & Warnings:
- Should not be discontinued abruptly, as it may cause rebound hypertension.
- May cause drowsiness; caution is advised when driving or operating machinery.
- Use with caution in patients with heart disease, kidney disease, or depression.
Possible Side Effects:
- Dry mouth and drowsiness
- Dizziness or lightheadedness
- Fatigue or headache
- Rebound hypertension if stopped suddenly
Storage & Packaging:
- Store below 30°C in a dry, dark place.
- Available in blister packs and bottle packaging as per market requirements.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP accredited facilities, designed as per EU-GMP standards to ensure high-quality production.
Global Export & Supply:
Aetos Life Care exports Clonidine 0.1 mg, 0.2 mg, 0.3 mg to Latin America, Africa, Asia, Europe, and CIS countries, offering high-quality and cost-effective pharmaceutical solutions worldwide.
