Description
Mechanism of Action:
✔ Inhibits the H+/K+ ATPase (proton pump) in gastric parietal cells—blocks the final step of acid production in the stomach.
✔ Reduces gastric acidity, providing prolonged relief from acid reflux and ulcers.
✔ Enhances the healing process of damaged esophageal and gastric mucosa.
Indications:
✔ Gastroesophageal Reflux Disease (GERD)
✔ Erosive Esophagitis
✔ Peptic Ulcer Disease (PUD) (including NSAID-induced ulcers)
✔ Helicobacter pylori eradication (in combination with antibiotics)
✔ Zollinger-Ellison Syndrome (Gastric Hypersecretion Disorder)
Key Benefits:
✅ Superior acid suppression compared to other PPIs.
✅ Provides long-lasting symptom relief with once-daily dosing.
✅ Effectively prevents ulcer formation in patients taking NSAIDs.
✅ Enhances the effectiveness of H. pylori eradication therapy.
✅ Improves overall digestive comfort and reduces heartburn episodes.
Dosage & Administration:
- GERD & Erosive Esophagitis: 20 mg to 40 mg once daily for 4–8 weeks.
- Peptic Ulcers (including NSAID-induced ulcers): 20 mg to 40 mg once daily for 4–8 weeks.
- H. pylori Eradication (as part of triple therapy): 20 mg twice daily with antibiotics for 7–14 days.
- Zollinger-Ellison Syndrome: 40 mg twice daily or as prescribed.
- Route of Administration: Oral.
- Food Intake: Best taken 1 hour before meals for maximum efficacy.
Precautions & Warnings:
- Prolonged use may lead to vitamin B12 deficiency.
- May increase the risk of Clostridium difficile-associated diarrhea.
- Caution in patients with osteoporosis due to potential fracture risk with long-term use.
- Not recommended for use in severe hepatic impairment without medical supervision.
- Avoid abrupt discontinuation to prevent rebound acid hypersecretion.
Possible Side Effects:
- Headache and dizziness
- Nausea, vomiting, or abdominal discomfort
- Constipation or diarrhea
- Flatulence (gas)
- Mild rash or allergic reaction (rare cases)
Storage & Packaging:
- Store below 30°C in a dry place, away from moisture and direct sunlight.
- Available in blister packs and bulk packaging, customizable for international clients.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP certified facilities, following EU-GMP standards to ensure global pharmaceutical quality compliance.
Global Export & Supply:
Aetos Life Care exports Esomeprazole Capsules 20 mg, 40 mg to Latin America, Africa, Asia, Europe, and CIS countries, offering high-quality and cost-effective gastroenterology solutions worldwide.
