Description
Mechanism of Action:
Isosorbide Dinitrate is converted into nitric oxide (NO) in the body, leading to:
✔ Vasodilation (Widening of blood vessels) → Improves oxygen supply to the heart.
✔ Reduced preload and afterload → Lessens strain on the heart.
✔ Decreased myocardial oxygen demand → Prevents angina episodes.
Indications:
✔ Angina Pectoris – Used for long-term prevention of chest pain.
✔ Heart Failure – Helps improve blood circulation in heart failure patients.
✔ Pulmonary Hypertension (Off-label use) – May assist in reducing pulmonary pressure.
Key Benefits:
✅ Effective angina prevention and management.
✅ Enhances heart function and reduces strain.
✅ Long-acting formula for better symptom control.
✅ Improves blood circulation and oxygen delivery to the heart.
Dosage & Administration:
- Isosorbide Dinitrate 10 mg – Taken two to three times daily or as prescribed.
- Route of Administration: Oral.
- Food Intake: Best taken on an empty stomach with water.
Precautions & Warnings:
- Avoid alcohol, as it may increase dizziness.
- Not suitable for patients with severe hypotension or recent heart attack.
- May cause tolerance if used continuously; dosing intervals should be followed strictly.
- Do not use with phosphodiesterase inhibitors (e.g., Sildenafil/Viagra) due to risk of severe hypotension.
Possible Side Effects:
- Headache (common and usually improves with continued use).
- Dizziness or low blood pressure.
- Flushing (warm sensation in the skin).
- Nausea or lightheadedness.
Storage & Packaging:
- Store at below 30°C in a dry, cool place.
- Available in blister packs and bottles as per customer demand.
- Bulk packaging available for international export.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP accredited facilities, meeting EU-GMP standards for quality assurance and global regulatory compliance.
Global Export & Supply:
Aetos Life Care exports Isosorbide Dinitrate 10 mg to Latin America, Africa, Asia, Europe, and CIS countries, ensuring high-quality pharmaceutical solutions for cardiovascular care.
