Description
Mechanism of Action:
✔ Reduces glucose production in the liver.
✔ Enhances insulin sensitivity, allowing better glucose utilization by muscles.
✔ Delays glucose absorption in the intestines.
✔ Does not cause hypoglycemia when used alone.
Indications:
✔ Type 2 Diabetes Mellitus (as monotherapy or in combination with other antidiabetic agents).
✔ Prevention of diabetes-related complications.
✔ Weight management in diabetic patients.
Key Benefits:
✅ Helps maintain stable blood sugar levels.
✅ Extended-release formulation reduces gastrointestinal discomfort.
✅ Supports weight loss and cardiovascular health.
✅ Does not cause low blood sugar (hypoglycemia) when used alone.
Dosage & Administration:
- Recommended Dosage:
- 500 mg once daily, titrated up to 2000 mg per day based on glycemic response.
- 750 mg or 1000 mg tablets may be used for higher-dose requirements.
- Route of Administration: Oral
- Food Intake: Take with food to reduce stomach upset.
- Do not crush or chew the extended-release tablets.
Precautions & Warnings:
- Not recommended for patients with severe kidney impairment.
- Monitor kidney function regularly (risk of lactic acidosis).
- May cause mild gastrointestinal discomfort (nausea, diarrhea, bloating) initially.
- Avoid excessive alcohol consumption.
Possible Side Effects:
- Nausea, vomiting, or diarrhea (usually improves over time).
- Abdominal discomfort.
- Lactic acidosis (rare but serious).
Storage & Packaging:
- Store below 30°C in a dry, dark place.
- Available in blister packs and bulk packaging.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP certified facilities, following EU-GMP standards for quality and efficacy.
Global Export & Supply:
Aetos Life Care exports Metformin Hydrochloride Extended-Release 500 mg, 750 mg, 1000 mg Tablets to Latin America, Africa, Asia, Europe, and CIS countries, offering effective and affordable diabetes management solutions worldwide.
