Description
Mechanism of Action:
✔ Blocks voltage-gated sodium channels, reducing neuronal excitability.
✔ Prevents repetitive firing of action potentials, stabilizing brain electrical activity.
✔ Suppresses excessive synaptic transmission, helping in seizure control.
Indications:
✔ Generalized Tonic-Clonic Seizures (Grand Mal Epilepsy)
✔ Complex Partial Seizures
✔ Status Epilepticus (Emergency Seizure Treatment, IV preferred)
✔ Seizure Prophylaxis in Neurosurgery & Head Trauma
✔ Trigeminal Neuralgia (off-label use for neuropathic pain relief)
Key Benefits:
✅ Effective long-term control of epilepsy
✅ Reduces seizure recurrence and severity
✅ Prevents post-traumatic and post-surgical seizures
✅ Once or twice-daily dosing for improved patient compliance
✅ Established safety profile in epilepsy management
Dosage & Administration:
- Recommended Dosage: 100 mg to 300 mg per day, as prescribed by a physician.
- Route of Administration: Oral.
- Food Intake: Can be taken with or without food, but consistency is recommended.
- Therapeutic drug monitoring may be required for optimal dosing.
Precautions & Warnings:
- Regular blood monitoring is required to maintain therapeutic levels.
- Avoid abrupt discontinuation, as it may trigger withdrawal seizures.
- May cause dizziness or drowsiness—avoid driving or operating machinery.
- Use with caution in patients with liver or kidney impairment.
- Can interact with multiple medications, including anticoagulants, birth control pills, and other anticonvulsants.
Possible Side Effects:
- Gingival hyperplasia (gum overgrowth)
- Dizziness, drowsiness, or lack of coordination
- Skin rash or hypersensitivity reactions (rare but serious)
- Increased hair growth (hirsutism)
- Long-term use may cause vitamin D deficiency and bone loss
Storage & Packaging:
- Store at below 30°C in a cool, dry place, away from moisture.
- Available in blister packs and bulk packaging as per market requirements.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP certified facilities, following EU-GMP guidelines to ensure global quality standards.
Global Export & Supply:
Aetos Life Care exports Phenytoin Tablets 100 mg to Latin America, Africa, Asia, Europe, and CIS countries, providing affordable and high-quality epilepsy treatments worldwide.
