Description
Mechanism of Action:
✔ Direct action on uterine smooth muscle – Stimulates strong, sustained uterine contractions to prevent postpartum hemorrhage.
✔ Vasoconstriction effect – Reduces blood loss by narrowing blood vessels.
✔ Serotonin & Dopaminergic Receptor Agonist – Induces smooth muscle contraction with minimal central nervous system effects.
Indications:
✔ Prevention & Treatment of Postpartum Hemorrhage (PPH)
✔ Management of Uterine Atony (Weak Uterine Contractions Postpartum)
✔ Facilitation of Placental Expulsion After Delivery
Key Benefits:
✅ Highly effective in preventing and managing postpartum bleeding
✅ Reduces uterine atony and minimizes postpartum complications
✅ Selective action on uterine smooth muscles with fewer systemic effects
✅ Rapid onset of action for immediate results
Dosage & Administration:
- Standard Dose: 0.125 mg orally, 3–4 times daily for up to 1 week post-delivery
• Route of Administration: Oral
• Food Intake: Can be taken with or without food
Precautions & Warnings:
- Contraindicated in hypertensive patients due to vasoconstriction effects.
• Not for use in pregnancy (only post-delivery) due to risk of excessive uterine contraction.
• May cause nausea, dizziness, or increased blood pressure – Monitor closely.
• Use with caution in patients with cardiovascular disorders, liver disease, or kidney impairment.
Possible Side Effects:
- Increased Blood Pressure (Hypertension)
• Nausea, Vomiting, or Abdominal Pain
• Headache & Dizziness
• Chest Pain or Shortness of Breath (rare cases)
Storage & Packaging:
- Store below 30°C in a dry place, away from direct sunlight.
• Available in blister packs & bulk packaging as per client requirements.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP-certified facilities, meeting EU-GMP quality standards for global distribution.
Global Export & Supply:
Aetos Life Care exports Methylergonovine Maleate 0.125 mg Tablets USP to Latin America, Africa, Asia, Europe, and CIS countries, ensuring high-quality and cost-effective pharmaceutical solutions worldwide.
