Description
Mechanism of Action:
- Fluconazole inhibits cytochrome P450-dependent fungal enzymes, preventing ergosterol formation, leading to disruption of fungal cell membranes and cell death.
Indications:
✔ Vaginal Candidiasis (Yeast Infection)
✔ Oropharyngeal and Esophageal Candidiasis
✔ Cryptococcal Meningitis
✔ Dermatophytosis (Ringworm, Athlete’s Foot, Jock Itch)
✔ Fungal Infections in Immunocompromised Patients
Key Benefits:
✅ Broad-spectrum antifungal action
✅ Single-dose treatment for vaginal candidiasis
✅ Highly effective against systemic and localized fungal infections
✅ Minimal side effects and well-tolerated
Dosage & Administration:
- Vaginal Candidiasis: 150 mg single dose
- Oropharyngeal Candidiasis: 50-100 mg once daily for 7-14 days
- Cryptococcal Meningitis: 400 mg on day 1, followed by 200-400 mg daily for 6-8 weeks
• Route of Administration: Oral
• Food Intake: Can be taken with or without food.
Precautions & Warnings:
- Use with caution in patients with hepatic impairment.
• May interact with warfarin, rifampin, and oral hypoglycemics.
• Avoid alcohol consumption during treatment.
• Not recommended during pregnancy and lactation unless prescribed by a doctor.
Possible Side Effects:
- Nausea, vomiting, or headache
• Abdominal discomfort or diarrhea
• Skin rash (rare)
• Liver enzyme elevation (monitor in prolonged use)
Storage & Packaging:
- Store at room temperature (below 30°C), away from direct sunlight.
• Available in blister packs and bottle packaging.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP-certified facilities, ensuring global quality standards compliant with EU-GMP regulations.
Global Export & Supply:
Aetos Life Care exports Fluconazole Capsules 150 mg to Latin America, Africa, Asia, Europe, and CIS countries, ensuring affordable and high-quality pharmaceutical solutions worldwide.
