Description
Mechanism of Action:
- Griseofulvin disrupts mitotic spindle formation in fungal cells by binding to tubulin, preventing cell division and growth.
• It gets incorporated into keratinocytes, making them resistant to fungal invasion, ensuring long-lasting protection.
Indications:
✔ Tinea Capitis (Scalp Ringworm)
✔ Tinea Corporis (Body Ringworm)
✔ Tinea Pedis (Athlete’s Foot)
✔ Tinea Cruris (Jock Itch)
✔ Tinea Unguium (Onychomycosis – Nail Fungus)
Key Benefits:
✅ Highly effective against dermatophyte infections
✅ Targets fungal infections in skin, hair, and nails
✅ Prevents recurrence with prolonged action
✅ Oral administration offers systemic coverage
Dosage & Administration:
- Adults: 500-1000 mg per day (divided into 1-2 doses).
- Children (>2 years): 10-20 mg/kg per day.
- Duration: 2-6 weeks (for skin infections), up to 12 months (for nail infections).
• Route of Administration: Oral
• Food Intake: Best taken with fatty foods (milk, cheese, or oil-rich foods) to enhance absorption.
Precautions & Warnings:
- Contraindicated in patients with liver disease, porphyria, and lupus.
• Avoid alcohol consumption during treatment due to liver metabolism concerns.
• Not recommended during pregnancy and breastfeeding.
• May cause photosensitivity – avoid prolonged sun exposure.
Possible Side Effects:
- Nausea, vomiting, diarrhea
• Headache and dizziness
• Skin rash or allergic reactions
• Liver enzyme changes (monitor in prolonged use cases)
Storage & Packaging:
- Store in a cool, dry place (below 30°C), away from direct sunlight.
• Available in blister packs and bulk packaging as per client requirements.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP accredited facilities, following EU-GMP quality standards for global export.
Global Export & Supply:
Aetos Life Care supplies Griseofulvin 500 mg Tablets to Latin America, Africa, Asia, Europe, and CIS countries, ensuring a cost-effective and high-quality antifungal treatment.
