Description
Mechanism of Action:
- Inhibits ergosterol synthesis, disrupting fungal cell membrane integrity.
• Prevents fungal replication and growth, leading to the elimination of infection.
Indications:
✔ Fungal skin infections (Dermatophytosis, Ringworm, Tinea, Pityriasis versicolor)
✔ Systemic fungal infections (Blastomycosis, Histoplasmosis, Coccidioidomycosis)
✔ Mucosal candidiasis (Oral thrush, Vaginal yeast infections)
✔ Seborrheic dermatitis (Dandruff-related fungal infections)
Key Benefits:
✅ Broad-spectrum antifungal coverage
✅ Effective for skin, mucosal, and systemic fungal infections
✅ Oral administration for systemic action
✅ Long-lasting antifungal protection
Dosage & Administration:
- Adults: 200-400 mg once daily.
- Children (>2 years): 3-6 mg/kg body weight per day.
- Duration: 2-6 weeks, depending on infection type.
• Route of Administration: Oral
• Food Intake: Best taken with food to enhance absorption.
Precautions & Warnings:
- Contraindicated in patients with liver disease – monitor liver enzymes in long-term use.
• Avoid alcohol and hepatotoxic drugs due to liver metabolism concerns.
• Not recommended during pregnancy and breastfeeding unless prescribed by a physician.
• May cause hormonal imbalance due to inhibition of steroidogenesis.
Possible Side Effects:
- Nausea, vomiting, and abdominal pain
• Liver enzyme elevation and hepatitis (rare but serious)
• Hormonal disturbances (gynecomastia, menstrual irregularities)
• Dizziness and headache
Storage & Packaging:
- Store in a cool, dry place (below 30°C), away from direct sunlight.
• Available in blister packs and bulk packaging as per client requirements.
Manufacturing & Regulatory Compliance:
Manufactured by Aetos Life Care in WHO-GMP accredited facilities, following EU-GMP quality standards for international supply.
Global Export & Supply:
Aetos Life Care exports Ketoconazole 200 mg Tablets to Latin America, Africa, Asia, Europe, and CIS countries, ensuring a cost-effective, high-quality antifungal solution.
